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Catalog Number | orb106931 |
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Category | Antibodies |
Description | Rabbit polyclonal to TAS2R43. Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May acts as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity). |
Species/Host | Rabbit |
Clonality | Polyclonal |
Clone Number | RB42224 |
Tested applications | WB |
Reactivity | Human |
Isotype | Rabbit IgG |
Immunogen | Synthetic Peptide |
Dilution range | WB: 1:1000 |
Form/Appearance | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Conjugation | Unconjugated |
MW | 35599 |
Target | TAS2R43 |
UniProt ID | P59537 |
NCBI | NP_795365.2 |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles |
Alternative names | anti TAS2R43 antibody, anti Taste receptor type 2 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
TAS2R43 Antibody (Center) western blot analysis in T47D cell line lysates (35 ug/lane). This demonstrates the TAS2R43 antibody detected the TAS2R43 protein (arrow).