TAO Kinase inhibitor 1

• Catalog Number: orb757621
• Category: Small Molecules
• Description: TAOK inhibitor 43 is a novel potent, selective, ATP-competitive TAO Kinase (TAOK) inhibitor with IC50 of 11 and 15 nM against TAOK1 and TAOK2, respectively; increases the mitotic population, the percentages of mitotic cells displaying amplified centrosomes and multipolar spindles, induces cell death, and inhibits cell growth in centrosome-amplified SKBR3 or BT549 breast cancer cell models.
• CAS Number: [850467-66-2]
• MW: 384.47
• SMILES: O=C(CNC(C1=CC=C(C2=CC=CC=C2)C=C1)=O)NC(CCC3)C4=C3C=CC=C4
• Formula: C₂₅H₂₄N₂O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.