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Catalog Number | orb1304813 |
---|---|
Category | Small Molecules |
Description | Tanshinone IIA sulfonate sodium |
CAS Number | 69659-80-9 |
Purity | 99.90% |
MW | 396.39 |
SMILES | Cc1c(oc2c1C(=O)C(=O)c1c2ccc2c1CCCC2(C)C)S(=O)(=O)[O-].[Na+] |
Formula | C19H17NaO6S |
Biological Activity | Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor P2X7. Tanshinone IIA sulfonate sodium (12.5 μM) inhibits hypoxia-induced PKG and PPAR-γ downregulation in PASMCs and distal pulmonary arteries of rats. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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