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Catalog Number | orb1307840 |
---|---|
Category | Small Molecules |
Description | Tandutinib |
CAS Number | 387867-13-2 |
Purity | 99.83% |
MW | 562.7 |
SMILES | O(C)C1=CC=2C(=NC=NC2C=C1OCCCN3CCCCC3)N4CCN(C(NC5=CC=C(OC(C)C)C=C5)=O)CC4 |
Formula | C31H42N6O4 |
Biological Activity | Tandutinib (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and > 100-fold selectivity for the same target versus FGFR, EGFR, and KDR. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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