TAK-243

• Catalog Number: orb1307707
• Category: Small Molecules
• Description: TAK-243
• CAS Number: 1450833-55-2
• Purity: 98.93%
• MW: 519.52
• SMILES: N(C=1N2C(=CC(=N2)C3=CC(SC(F)(F)F)=CC=C3)N=CC1)[C@@H]4C[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]4O
• Formula: C₁₉H₂₀F₃N₅O₅S₂
• Biological Activity: TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM). TAK-243 blocks ubiquitin binding and disrupts mono-ubiquitin signaling as well as overall protein ubiquitination. TAK-243 exhibits antitumor activity and promotes apoptosis.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.