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Catalog Number | orb1692522 |
---|---|
Category | Small Molecules |
Description | T 26c disodium salt |
CAS Number | 869298-22-6 |
MW | 525.49 |
SMILES | [Na].[Na].COc1cccc(CNC(=O)c2nc(=O)c3c(COCc4ccc(cc4)C(O)=O)csc3[nH]2)c1jcExt:v:0:0,1:0 |
Formula | C24H21N3Na2O6S |
Biological Activity | Highly potent and selective MMP13 inhibitor (IC50 = 6.9 pM). Exhibits > 2600-fold selectivity for MMP13 over related MMPs. Inhibits degradation of bovine nasal septum cartilage explants in vitro . Orally bioavailable. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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