SZL P1-41

• Catalog Number: orb1304331
• Category: Small Molecules
• Description: SZL P1-41
• CAS Number: 222716-34-9
• Purity: 99.82%
• MW: 420.52
• SMILES: CCC1=C(O)C(CN2CCCCC2)=C2OC=C(C3=NC4=C(S3)C=CC=C4)C(=O)C2=C1
• Formula: C₂₄H₂₄N₂O₃S
• Biological Activity: SZL P1-41, a skp2 inhibitor, can prevent assembly of Skp2-Skp1 complexes. It selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF complexes. It also inhibits Skp2-mediated p27 and Akt ubiquitination in vivo and in vitro. It suppresses the survival of Y cells and Y stem cells by triggering cell senescence and inhibiting glycolysis. It exhibits antitumor effects in multiple animal models and Y cell lines.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.