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Syk Inhibitor II dihydrochloride dihydrate

Syk Inhibitor II dihydrochloride dihydrate

Catalog Number: orb1687352

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Catalog Numberorb1687352
CategorySmall Molecules
DescriptionSyk Inhibitor II dihydrochloride dihydrate
CAS Number1965323-05-0
Purity98%
MW449.26
SMILESO=C(C1=CN=C(NCCN)N=C1NC2=CC=CC(C(F)(F)F)=C2)N.Cl.O.Cl.O
FormulaC14H21Cl2F3N6O3
Biological ActivitySyk Inhibitor II dihydrochloride dihydrate is a potent, high selective and ATP-competitive Syk inhibitor with an IC 50 of 41 nM. Syk Inhibitor II dihydrochloride dihydrate inhibits 5-HT release from RBL-cells with an IC 50 of 460 nM. Syk Inhibitor II dihydrochloride dihydrate shows less potent against other kinases and has anti-allergic effect [1].
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.