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Catalog Number | orb1687352 |
---|---|
Category | Small Molecules |
Description | Syk Inhibitor II dihydrochloride dihydrate |
CAS Number | 1965323-05-0 |
Purity | 98% |
MW | 449.26 |
SMILES | O=C(C1=CN=C(NCCN)N=C1NC2=CC=CC(C(F)(F)F)=C2)N.Cl.O.Cl.O |
Formula | C14H21Cl2F3N6O3 |
Biological Activity | Syk Inhibitor II dihydrochloride dihydrate is a potent, high selective and ATP-competitive Syk inhibitor with an IC 50 of 41 nM. Syk Inhibitor II dihydrochloride dihydrate inhibits 5-HT release from RBL-cells with an IC 50 of 460 nM. Syk Inhibitor II dihydrochloride dihydrate shows less potent against other kinases and has anti-allergic effect [1]. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |