Streptozocin

• Catalog Number: orb1308404
• Category: Small Molecules
• Description: Streptozocin
• CAS Number: 18883-66-4
• Purity: 99.90%
• MW: 265.22
• SMILES: CN(N=O)C(=O)NC1C(O)OC(CO)C(O)C1O
• Formula: C₈H₁₅N₃O₇
• Biological Activity: Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used in the construction of animal models of type 1 diabetes. The product is unstable in solution and is recommended to be dispensed now.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

References

VI Sevastianov, AS Ponomareva, NV Baranova A Tissue-Engineered Construct Based on a Decellularized Scaffold and the Islets of Langerhans: A Streptozotocin-Induced Diabetic Model Life, (2024)

PubMed: