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Catalog Number | orb1737997 |
---|---|
Category | Small Molecules |
Description | Streptonigrin (racemate) |
CAS Number | 1079893-79-0 |
Purity | 0.98 |
MW | 506.46 |
SMILES | NC=1C(=C(C)C(C(O)=O)=NC1C=2N=C3C(=CC2)C(=O)C(OC)=C(N)C3=O)C4=C(O)C(OC)=C(OC)C=C4 |
Formula | C25H22N4O8 |
Biological Activity | Streptonigrin is an aminoquinone antitumor and antibacterial antibiotic produced by Streptomyces flocculus. Streptonigrin inhibits β-Catenin/Tcf signaling and shows cytotoxicity in β-catenin-activated cells. Streptonigrin induces delayed chromosomal instability involving interstitial telomeric sequences in Chinese hamster ovary cells. Note: Streptonigrin from natural resource is (-)-rotation, has CAS#3930-19-6 and is a R-isomer. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |