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Catalog Number | orb1299034 |
---|---|
Category | Small Molecules |
Description | SR-4835 |
CAS Number | 2387704-62-1 |
Purity | 99.41% |
MW | 499.36 |
SMILES | Cn1cc(cn1)-n1cnc2c(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)nc(nc12)N1CCOCC1 |
Formula | C21H20Cl2N10O |
Biological Activity | SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (TNBC) cells |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |