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Catalog Number | orb1692751 |
---|---|
Category | Small Molecules |
Description | Squarunkin A hydrochloride |
CAS Number | 2253744-55-5 |
Purity | 98% |
MW | 560.02 |
SMILES | Cl.CCOC(=O)N1CCC(CC1)Nc1c(NCCN2CCN(CC2)c2cccc(c2)C(F)(F)F)c(=O)c1=O |
Formula | C25H33ClF3N5O4 |
Biological Activity | Squarunkin A hydrochloride is a potent and selective UNC119-cargo interaction inhibitor. Squarunkin A hydrochloride selectively inhibits the binding of a myristoylated peptide representing the N-terminus of Src kinase to UNC119A with an IC50 value of 10 nm. Squarunkin A hydrochloride interferes with the activation of Src kinase in cells [1]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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