Spadin TFA

• Catalog Number: orb1981513
• Category: Small Molecules
• Description: Spadin TFA, a natural peptide originating from a propeptide in blood, acts as a powerful TREK-1 channel inhibitor with an IC 50 of 10 nM. It boosts dorsal raphe nucleus 5-HT neurotransmission in mice, activates hippocampal CREB, and promotes neurogenesis. This compound is useful for antidepressant research [1] [2].
• Purity: 98.00%
• MW: 2126.36
• Formula: C₉₂H₁₄₃F₃N₂₆O₂₄
• Biological Activity: Spadin TFA, a natural peptide originating from a propeptide in blood, acts as a powerful TREK-1 channel inhibitor with an IC 50 of 10 nM. It boosts dorsal raphe nucleus 5-HT neurotransmission in mice, activates hippocampal CREB, and promotes neurogenesis. This compound is useful for antidepressant research [1] [2].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.