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Catalog Number | orb2276815 |
---|---|
Category | Small Molecules |
Description | Sp-Uridine-5'-O-(1-thiotriphosphate) (Sp-UTP-α-S) acts as a nucleotide agonist for purinergic Y2 (P2Y2) and P2Y4 receptors, efficiently inducing inositol phosphate accumulation in 1321N1 astrocytoma cells that express these receptors, with half-maximal effective concentrations (EC50s) of 14 µM and 81 µM, respectively. |
Purity | 98.00% |
MW | 588.14 |
SMILES | [S-][P@@](OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=CC(NC2=O)=O)O1)(OP(OP([O-])([O-])=O)([O-])=O)=O.[Na+].[Na+].[Na+].[Na+] |
Formula | C9H11N2O14P3S.4Na |
Biological Activity | Sp-Uridine-5'-O-(1-thiotriphosphate) (Sp-UTP-α-S) acts as a nucleotide agonist for purinergic Y2 (P2Y2) and P2Y4 receptors, efficiently inducing inositol phosphate accumulation in 1321N1 astrocytoma cells that express these receptors, with half-maximal effective concentrations (EC50s) of 14 µM and 81 µM, respectively. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |