Sorafenib

• Catalog Number: orb1310944
• Category: Small Molecules
• Description: Sorafenib
• CAS Number: 284461-73-0
• Purity: 99.61%
• MW: 464.82
• SMILES: O(C=1C=C(C(NC)=O)N=CC1)C2=CC=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2
• Formula: C₂₁H₁₆ClF₃N₄O₃
• Biological Activity: Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. Sorafenib has antitumor activity and can induce autophagy and apoptosis as well as agonistic ferroptosis.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.