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Catalog Number | orb1298954 |
---|---|
Category | Small Molecules |
Description | SNC 80 |
CAS Number | 156727-74-1 |
Purity | 98.67% |
MW | 449.63 |
SMILES | [C@H](N1[C@@H](C)CN(CC=C)[C@H](C)C1)(C2=CC(OC)=CC=C2)C3=CC=C(C(N(CC)CC)=O)C=C3 |
Formula | C28H39N3O2 |
Biological Activity | SNC 80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist, Ki = 1.78 nM, IC50 = 2.73 nM. SNC80 also selectively activates μ-δ heteromer in HEK293 cells with an EC50 of 52.8 nM. SNC80 shows antinociceptive, antihyperalgesic and antidepressant‐like effects. SNC80 has the potential for multiple headache disorders treatment. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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