SNAIL antibody

• Catalog Number: orb33657
• Category: Antibodies
• Description: Rabbit polyclonal antibody to SNAIL belongs to the snail C2H2-type zinc-finger protein family. Snail has its highest expression in kidney, regulating epithelial-to-mesenchymal transitions and cell migration. Snail family members influence cell behavior during development and diseases such as metastatic cancer, where they act primarily as survival factors and inducers of cell movement.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Clone Number: RB01400
• Tested applications: IHC-P, WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: Synthetic Peptide
• Dilution range: WB: 1:1000, IHC-P: 1:10-50
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• MW: 29083
• Target: SNAI1
• UniProt ID: O95863
• NCBI: NP_005976.2
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Alternative names: Anti-"Zinc finger protein SNAI1 antibody, anti-Sna
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

References

Wen, Yu-Ching et al. Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy Clin Chim Acta, 431, 169-173 (2014)

PubMed: 24513541

Chiu, Jen-Hwey et al. Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers J Transl Med, 15, 97 (2017)

PubMed: 28472954

Immunohistochemical analysis of formalin-fixed and paraffin-embedded human spleen tissue using SNAIL antibody

Western blot analysis of HepG2 cells using SNAIL antibody

Western blot analysis of 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SNAIL gene (Lane 2) using SNAIL antibody