Smurf1-IN-A01

• Catalog Number: orb1307737
• Category: Small Molecules
• Description: Smurf1-IN-A01
• CAS Number: 1007647-73-5
• Purity: 99.54%
• MW: 512.93
• SMILES: S(=O)(=O)(C1=CC(C(F)(F)F)=C(Cl)C=C1)N2CCN(C(=O)C3=CC=C(C=C3)N4C(C)=CC=N4)CC2
• Formula: C₂₂H₂₀ClF₃N₄O₃S
• Biological Activity: Smurf1-IN-A01 (A01) is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM). It increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.