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SLU-PP-332
Catalog Number: orb1819063
| Catalog Number | orb1819063 |
|---|---|
| Category | Small Molecules |
| Description | SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRα, ERRβ, and ERRγ, exhibiting EC50 values of 98, 230, and 430 nM, respectively. SLU-PP-332 enhances mitochondrial function and cellular respiration, increases type IIa oxidized skeletal muscle fibers, and enhances exercise tolerance in skeletal muscle cell lines. It has potential applications in the study of metabolic diseases, improvement of muscle function, and amelioration of metabolic disorders and aging. |
| CAS Number | 303760-60-3 |
| Purity | 98.30% |
| MW | 290.32 |
| SMILES | C(=NNC(=O)C1=CC=C(O)C=C1)C2=CC3=C(C=C2)C=CC=C3 |
| Formula | C18H14N2O2 |
| Target | ERRγ:430 nM (EC50), ERRβ:230 nM (EC50), ERRα:98 nM (EC50) |
| Biological Activity | SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRα, ERRβ, and ERRγ with EC50 values of 98, 230, and 430 nM, respectively.SLUPP-332 enhances mitochondrial function and cellular respiration, increases type IIa oxidized skeletal muscle fibers, and enhances exercise tolerance in skeletal muscle cell lines. SLU-PP-332 has the potential to be used in the study of metabolic diseases and improvement of muscle function, and may be used to ameliorate metabolic disorders and aging. |
| Storage | Powder: -20°C for 3 years, In solvent: -80°C for 1 year |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
CAS: 303760-60-3
