SLIGRL-NH2

• Catalog Number: orb1147039
• Category: Proteins
• Description: PAR2 activating peptide; Peptides.
• CAS Number: 171436-38-7
• Modifications: C-terminal amide.
• Structure: H-Ser-Leu-Ile-Gly-Arg-Leu-NH2
• Target Areas: Protease activated receptors
• Form/Appearance: Freeze dried solid
• Purity: > 95% by hplc
• MW: 656.82 Da
• Formula: C₂₉H₅₆N₁₀O₇
• Solubility (25°C): Soluble to 1 mg/ml in water
• Protein Sequence: H-Ser-Leu-Ile-Gly-Arg-Leu-NH2
• Storage: Store dry, frozen and in the dark
• Alternative names: , 171436-38-7, PAR-2 activation peptide, SL-NH2, S
• Background: SLIGRL-NH2 is an agonist peptide derived from the N-terminus (aas 39-44) of protease-activated receptor 2 (PAR2). SLIGRL-NH2 activates PAR2 with an EC50 of approximately 5 µM and through its effects on PAR2 it stimulates gastric and intestinal smooth muscle contraction. SLIGRL-NH2 is a pruritogen and causes scratching behaviour in mice.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.