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Catalog Number | orb692102 |
---|---|
Category | Small Molecules |
Description | SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC50 of 2 μM for GST-hSK. SKI V potently inhibits PI3K with an IC50 of 6 μM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity[1][2]. |
CAS Number | [24418-86-8] |
MW | 254.23 |
SMILES | O=C1C2C(=CC=CC=2)O/C/1=C\C1C=C(O)C(O)=CC=1 |
Formula | C15H10O4 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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