SIRT5 inhibitor 7

• Catalog Number: orb1944441
• Category: Small Molecules
• Description: SIRT5 inhibitor 7 (compound 58), a selective and substrate-competitive SIRT5 inhibitor, exhibits anti-inflammatory properties by modulating protein succinylation and attenuating pro-inflammatory cytokine release. It demonstrates renal protective effects and is active in vivo, showing efficacy in AKI mouse models subjected to lipopolysaccharide (LPS) and cecal ligation/perforation (CLP)-induced sepsis-related acute kidney injury [1].
• CAS Number: 2951090-00-7
• Purity: 98.00%
• MW: 582.12
• SMILES: N(CCCNC(NCCC(O)=O)=S)C=1C(C(=O)N2C[C@H](CC2)C3=CC=CC=C3)=CN=C(NC4=C(Cl)C=CC=C4)N1
• Formula: C₂₈H₃₂ClN₇O₃S
• Biological Activity: SIRT5 inhibitor 7 (compound 58), a selective and substrate-competitive SIRT5 inhibitor, exhibits anti-inflammatory properties by modulating protein succinylation and attenuating pro-inflammatory cytokine release. It demonstrates renal protective effects and is active in vivo, showing efficacy in AKI mouse models subjected to lipopolysaccharide (LPS) and cecal ligation/perforation (CLP)-induced sepsis-related acute kidney injury [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.