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Catalog Number | orb654506 |
---|---|
Category | Small Molecules |
Description | SHP504 is a distinct, allosteric site 2 SHP2 inhibitor with IC50 of 21 uM (SHP2 1-525), and selective over the phosphatase domain (SHP2 PTP IC50>100 uM).downregulates DUSP6 mRNA, a downstream MAPK pathway marker, in KYSE-520 cancer cells. |
CAS Number | [2222280-83-1] |
Purity | > 98%,Standard References |
MW | 446.847 |
SMILES | C(O)(=O)C1=CC=C(O)C(C2N3C4=C(C=CC=C4)C(=O)N(CC4=CC=CC=C4Cl)C3=NN=2)=C1 |
Formula | C23H15ClN4O4 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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