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Catalog Number | orb1308761 |
---|---|
Category | Small Molecules |
Description | Shield-1 |
CAS Number | 914805-33-7 |
Purity | 99.22% |
MW | 748.9 |
SMILES | [C@H](C(=O)N1[C@H](C(O[C@H](CCC2=CC(OC)=C(OC)C=C2)C3=CC(OCCN4CCOCC4)=CC=C3)=O)CCCC1)(CC)C5=CC(OC)=C(OC)C(OC)=C5 |
Formula | C42H56N2O10 |
Biological Activity | Shield-1 is a specific, high-affinity and cell-permeant ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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