SGC2085 Hydrochloride

• Catalog Number: orb746295
• Category: Small Molecules
• Description: SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor with an IC50 of 50 nM and more than undred-fold selectivity over other PRMTs. CARM1 is an important positive modulator of Wnt/β-catenin transcription and neoplastic transformation in colorectal cancer as well as a critical factor in estrogen-stimulated breast cancer growth, and its depletion results in decreased proliferation of myeloid leukemia cells in vivo.
• CAS Number: [1821908-49-9]
• MW: 348.87
• SMILES: C[C@H](N)C(NCC1=CC=C(OC2=CC(C)=CC(C)=C2)C(C)=C1)=O.[H]Cl
• Formula: C₁₉H₂₅ClN₂O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.