SGC agonist 2

• Catalog Number: orb1687133
• Category: Small Molecules
• Description: SGC agonist 2
• CAS Number: 2735713-77-4
• Purity: 98%
• MW: 461.42
• SMILES: O=C1[C@@]2(C3=C(NC(=NC3=NC(=O)C2(C)C)C=4C=5C(N(CC6=C(F)C=CC=C6)N4)=NC=C(F)C5)N1)[H]
• Formula: C₂₃H₁₇F₂N₇O₂
• Biological Activity: SGC agonist 2 is a potent agonist of soluble guanylate cyclase ( SGC ). Soluble guanylate cyclase is a key signal transduction enzyme in the NO-sGC-cGMP signaling pathway. SGC agonist 2 has the potential for the research of cardiovascular disease (heart failure, pulmonary hypertension, angina, myocardial infarction) and fibrotic diseases (renal fibrosis, systemic sclerosis) (extracted from patent WO2021219088A1, compound 031) [1].
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.