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Catalog Number | orb1687133 |
---|---|
Category | Small Molecules |
Description | SGC agonist 2 |
CAS Number | 2735713-77-4 |
Purity | 98% |
MW | 461.42 |
SMILES | O=C1[C@@]2(C3=C(NC(=NC3=NC(=O)C2(C)C)C=4C=5C(N(CC6=C(F)C=CC=C6)N4)=NC=C(F)C5)N1)[H] |
Formula | C23H17F2N7O2 |
Biological Activity | SGC agonist 2 is a potent agonist of soluble guanylate cyclase ( SGC ). Soluble guanylate cyclase is a key signal transduction enzyme in the NO-sGC-cGMP signaling pathway. SGC agonist 2 has the potential for the research of cardiovascular disease (heart failure, pulmonary hypertension, angina, myocardial infarction) and fibrotic diseases (renal fibrosis, systemic sclerosis) (extracted from patent WO2021219088A1, compound 031) [1]. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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