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Semagacestat
Catalog Number: orb181318
| Catalog Number | orb181318 |
|---|---|
| Category | Small Molecules |
| Description | Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, also inhibits Notch signaling with IC50 of 14.1 nM. |
| CAS Number | [425386-60-3] |
| MW | 361.44 |
| SMILES | O=C([C@H]1NC([C@@H](NC([C@H](C(C)C)O)=O)C)=O)N(CCC2=C1C=CC=C2)C |
| Formula | C19H27N3O4 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 1
Semagacestat [orb1225074]
> 98% (HPLC)
425386-60-3
50 mg, 100 mg, 1 g, 500 mg, 200 mg, 2 mg, 5 mg, 10 mg, 25 mgSemagacestat [orb1301052]
99.11%
425386-60-3
361.44
C19H27N3O4
10 mg, 25 mg, 50 mg, 100 mg, 5 mg, 2 mg, 1 mL*10mM (in DMSO)
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