Semagacestat

• Catalog Number: orb1301052
• Category: Small Molecules
• Description: Semagacestat
• CAS Number: 425386-60-3
• Purity: 99.11%
• MW: 361.44
• SMILES: N(C([C@@H](NC([C@H](C(C)C)O)=O)C)=O)[C@H]1C=2C(CCN(C)C1=O)=CC=CC2
• Formula: C₁₉H₂₇N₃O₄
• Biological Activity: Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.