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Catalog Number | orb1298899 |
---|---|
Category | Small Molecules |
Description | SC-43 |
CAS Number | 1400989-25-4 |
Purity | 99.26% |
MW | 431.8 |
SMILES | FC(F)(F)C1=C(Cl)C=CC(NC(=O)NC2=CC(OC3=CC=C(C=C3)C#N)=CC=C2)=C1 |
Formula | C21H13ClF3N3O2 |
Biological Activity | SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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