SBP1

• Catalog Number: orb1140627
• Category: Proteins
• Description: Binds to the SARS-CoV-2 receptor binding domain; Peptides.
• Modifications: C terminal amide.
• Structure: H-Ile-Glu-Glu-Gln-Ala-Lys-Thr-Phe-Leu-Asp-Lys-Phe-Asn-His-Glu-Ala-Glu-Asp-Leu-Phe-Tyr-Gln-Ser-NH2
• Target Areas: Protein-protein interactions, Angiotensin converting enzyme, Antivirals
• Form/Appearance: Freeze dried solid
• Purity: > 95% by HPLC
• MW: 2802.05 Da
• Formula: C₁₂₇H₁₈₅N₃₁O₄₁
• Solubility (25°C): Soluble to 1 mg/ml in water
• Protein Sequence: IEEQAKTFLDKFNHEAEDLFYQS-NH2
• Storage: Store desiccated, frozen and in the dark
• Alternative names: ACE2, COVID-19CV050, H-IEEQAKTFLDKFNHEAEDLFYQS-NH2
• Background: SBP1 is a 23 amino acid fragment of the angiotensin-converting enzyme 2 (ACE2) peptidase domain (PD) α1 helix, a key domain for the interaction of ACE2 with the severe acute respiratory syndrome coronavirus receptor binding domain (SARS-CoV-2-RBD). SBP1 binds to the SARS-CoV-2-RBD with an affinity comparable with the corresponding spike protein of SARS-CoV, and can potentially block the mechanism by which SARS-CoV-2 enters into cells. SBP1 offers an opportunity for therapeutic intervention in COVID-19.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.