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Catalog Number | orb1705004 |
---|---|
Category | Small Molecules |
Description | SB-505124 hydrochloride |
CAS Number | 356559-13-2 |
MW | 371.86 |
SMILES | Cl.N=1C(=CC=CC1C)C=2N=C(NC2C=3C=CC=4OCOC4C3)C(C)(C)C |
Formula | C20H22ClN3O2 |
Biological Activity | SB-505124 hydrochloride functions as a selective, concentration-dependent inhibitor targeting TGF-β Receptor type I (ALK4, ALK5, ALK7), exhibiting IC50 values of 129 nM for ALK4 and 47 nM for ALK5. Notably, it does not affect ALK1, 2, 3, or 6. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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