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    SB-505124 hydrochloride

    SB-505124 hydrochloride

    Catalog Number: orb1705004

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    Catalog Numberorb1705004
    CategorySmall Molecules
    DescriptionSB-505124 hydrochloride
    CAS Number356559-13-2
    MW371.86
    SMILESCl.N=1C(=CC=CC1C)C=2N=C(NC2C=3C=CC=4OCOC4C3)C(C)(C)C
    FormulaC20H22ClN3O2
    Biological ActivitySB-505124 hydrochloride functions as a selective, concentration-dependent inhibitor targeting TGF-β Receptor type I (ALK4, ALK5, ALK7), exhibiting IC50 values of 129 nM for ALK4 and 47 nM for ALK5. Notably, it does not affect ALK1, 2, 3, or 6.
    NoteFor research use only
    Expiration Date12 months from date of receipt.
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