SB 203580 sulfone

• Catalog Number: orb2283711
• Category: Small Molecules
• Description: SB 203580 sulfone, an analog of the p38 MAP kinase inhibitor SB 203580, inhibits IL-1 production in monocytes and binds competitively with CSAID binding proteins (CSBP), inhibiting stress response signaling. It exhibits an IC50 of 0.2 μM for IL-1 inhibition and 0.03 μM for CSBP-mediated signaling inhibition [1].
• CAS Number: 152121-46-5
• Purity: 98.00%
• MW: 393.43
• SMILES: FC1=CC=C(C2=C(N=C(N2)C3=CC=C(S(C)(=O)=O)C=C3)C=4C=CN=CC4)C=C1
• Formula: C₂₁H₁₆FN₃O₂S
• Biological Activity: SB 203580 sulfone, an analog of the p38 MAP kinase inhibitor SB 203580, inhibits IL-1 production in monocytes and binds competitively with CSAID binding proteins (CSBP), inhibiting stress response signaling. It exhibits an IC50 of 0.2 μM for IL-1 inhibition and 0.03 μM for CSBP-mediated signaling inhibition [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.