SARS-CoV-2 3CLpro/3C-like protease Protein (His)

• Catalog Number: orb1954151
• Category: Proteins
• Description: 3C-like protease (3CLpro) is the main protease of Humann Coronavirus. 3C-like protease (3CLpro) is a key enzyme, as it cleaves several sites to produce non-structural proteins that are essential for genome replication and Coronavirus virion production, such as an RNA-dependent RNA polymerase, a helicase, ribonucleases and 3CLpro itself, from two types of polyproteins (pp1a and pp1ab). SARS-CoV 3CLpro exists as a homodimer and each protomer has an active site. SARS-CoV-2 3CLpro/3C-like protease Protein (His) is expressed in Baculovirus insect cells. The predicted molecular weight is 35.31 kDa and the accession number is YP_009725295.1.
• Tag: N-His
• Purity: 98.00%
• MW: 35.31 kDa (predicted)
• UniProt ID: YP_009725295.1
• Expression System: Baculovirus Insect Cells
• Biological Origin: SARS-CoV-2
• Biological Activity: 3C-like protease (3CLpro) is the main protease of Humann Coronavirus. 3C-like protease (3CLpro) is a key enzyme, as it cleaves several sites to produce non-structural proteins that are essential for genome replication and Coronavirus virion production, such as an RNA-dependent RNA polymerase, a helicase, ribonucleases and 3CLpro itself, from two types of polyproteins (pp1a and pp1ab). SARS-CoV 3CLpro exists as a homodimer and each protomer has an active site. SARS-CoV-2 3CLpro/3C-like protease Protein (His) is expressed in Baculovirus insect cells. The predicted molecular weight is 35.31 kDa and the accession number is YP_009725295.1.
• Expression Region: A DNA sequence encoding the SARS-CoV-2 (2019-nCoV) 3CL Protease (YP_009725295.1) (Ser3264-Gln3569) was expressed with a N-terminal polyhistidine tagged. Predicted N terminal: Met
• Storage: -20°C
• Note: For research use only
• Application notes: A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
• Expiration Date: 6 months from date of receipt.