SAR-439859

• Catalog Number: orb1089364
• Category: Small Molecules
• Description: SAR439859 is an orally available, nonsteroidal selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD SAR439859 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells
• CAS Number: [2114339-57-8]
• MW: 554.4792104
• SMILES: ClC1C=C(C=CC=1C1CCCC2C=C(C(=O)O)C=CC=2C=1C1C=CC(=CC=1)O[C@H]1CCN(CCCF)C1)Cl
• Formula: C₃₁H₃₀CL₂FNO₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.