SAG dihydrochloride

• Catalog Number: orb1690570
• Category: Small Molecules
• Description: SAG dihydrochloride
• CAS Number: 2702366-44-5
• Purity: 98%
• MW: 562.98
• SMILES: O=C(C1=C(C2=CC=CC=C2S1)Cl)N([C@@H]3CC[C@H](CC3)NC)CC4=CC(C5=CC=NC=C5)=CC=C4.Cl.Cl
• Formula: C₂₈H₃₀Cl₃N₃OS
• Biological Activity: SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist ( EC 50 =3 nM; K d =59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.