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Catalog Number | orb1824393 |
---|---|
Category | Antibodies |
Description | The S-100 protein family consists of a group of calcium-binding proteins, that exhibit cell and tissue-specific expression. The expression levels of its members differ in various pathological conditions. The extracellular functions of the S-100 family may include the ability to enhance neurite outgrowth, involvement in inflammation and motility of tumor cells. S-100A13 is a 98 amino acid protein with 2 EF-hand calcium-binding domains. High levels of S-100A13 mRNA are present in skeletal muscle, heart, kidney, ovary, small intestine and pancreas. S-100A13 translocates in response to elevated intracellular calcium levels induced by Angiotensin II. S-100A13 co-localizes with S-100A1 on human chromosome 1q21.3, the site where the majority of S-100 proteins cluster. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | S100A13/7483 |
Tested applications | IHC-P |
Reactivity | Human |
Isotype | Mouse IgG2b, kappa |
Immunogen | A recombinant partial protein sequence (within amino acids 1-93) from the human protein was used as the immunogen for the S100A13 antibody. |
Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT |
Conjugation | Unconjugated |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Hazard Information | This S100A13 antibody is available for research use only. |
UniProt ID | Q99584 |
Storage | Aliquot the S100A13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
IHC staining of FFPE human spleen tissue with S100A13 antibody (clone S100A13/7483). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free S100A13 antibody (clone S100A13/7483) as confirmation of integrity and purity.
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