S-Ruxolitinib (INCB018424)

• Catalog Number: orb154739
• Category: Small Molecules
• Description: S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, > 130-fold selectivity for JAK1/2 versus JAK3. Phase 3.
• CAS Number: [941685-37-6]
• MW: 306.37
• SMILES: N#CC[C@@H](C1CCCC1)N2N=CC(C3=NC=NC4=C3C=CN4)=C2
• Formula: C₁₇H₁₈N₆
• Note: For research use only
• Expiration Date: 12 months from date of receipt.