RUNX-IN-1

• Catalog Number: orb2277781
• Category: Small Molecules
• Description: RUNX-IN-1, also known as Compound Conjugate 1, covalently attaches to RUNX-binding sequences, thereby preventing RUNX proteins from associating with their specific targets. This compound triggers p53-dependent apoptosis and suppresses the proliferation of cancer cells. Furthermore, RUNX-IN-1 has demonstrated efficacy in impeding tumor progression in PANC-1 xenograft mice [1].
• CAS Number: 2177285-35-5
• Purity: 98.00%
• MW: 1524.52
• SMILES: N(C(=O)C1=CC(NC(=O)C2=NC(NC(CCNC(CCCC3=CC=C(N(CCCl)CCCl)C=C3)=O)=O)=CN2C)=CN1C)C=4N=C(C(NC=5N=C(C(NCCCC(NC=6C=C(C(NC=7C=C(C(NC=8C=C(C(NC=9C=C(C(NCCCN(C)C)=O)N(C)C9)=O)N(C)C8)=O)N(C)C7)=O)N(C)C6)=O)=O)N(C)C5)=O)N(C)C4
• Formula: C₇₁H₈₈Cl₂N₂₄O₁₁
• Biological Activity: RUNX-IN-1, also known as Compound Conjugate 1, covalently attaches to RUNX-binding sequences, thereby preventing RUNX proteins from associating with their specific targets. This compound triggers p53-dependent apoptosis and suppresses the proliferation of cancer cells. Furthermore, RUNX-IN-1 has demonstrated efficacy in impeding tumor progression in PANC-1 xenograft mice [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.