Rosuvastatin Sodium

• Catalog Number: orb1686613
• Category: Small Molecules
• Description: Rosuvastatin Sodium
• CAS Number: 147098-18-8
• MW: 503.52
• SMILES: CC(C1=NC(N(S(=O)(C)=O)C)=NC(C2=CC=C(F)C=C2)=C1/C=C/[C@@H](O)C[C@@H](O)CC([O-])=O)C.[Na+]
• Formula: C₂₂H₂₇FN₃NaO₆S
• Biological Activity: Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor (IC50: 11 nM) that effectively blocks hERG currents (IC50: 195 nM). Rosuvastatin Sodium reduces the expression of mature hERG and inhibits the interaction of heat shock protein 70 (Hsp70) with hERG protein.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.