Rosiptor acetate

• Catalog Number: orb1679069
• Category: Small Molecules
• Description: Rosiptor acetate
• CAS Number: 782487-29-0
• Purity: 98%
• MW: 381.55
• SMILES: C(C)(O)=O.C[C@@]1([C@@]2([C@@H](CN)[C@]3([C@](C)(CC2)C(=C)CC3)[H])[H])[C@@H](CO)C[C@@H](O)CC1
• Formula: C₂₂H₃₉NO₄
• Biological Activity: Rosiptor is a potent and selective SHIP1 activator. AQX-1125 inhibits Akt phosphorylation in SHIP1-proficient but not in SHIP1-deficient cells, reduces cytokine production in splenocytes, inhibits the activation of mast cells and inhibits human leukocyte chemotaxis. AQX-1125 suppresses leukocyte accumulation and inflammatory mediator release in rodent models of pulmonary inflammation and allergy.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.