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Catalog Number | orb2277919 |
---|---|
Category | Small Molecules |
Description | RORγt inverse agonist 31 |
MW | 555.36 |
Formula | C23H15Cl2F3N4O3S |
Biological Activity | RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), exhibiting an inhibitory concentration (IC50) of 0.428 μM. It has demonstrated efficacy in mitigating Imiquimod-induced psoriasis severity in murine models [1]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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