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    RORγt inverse agonist 31

    RORγt inverse agonist 31

    Catalog Number: orb2277919

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    Catalog Numberorb2277919
    CategorySmall Molecules
    DescriptionRORγt inverse agonist 31
    MW555.36
    FormulaC23H15Cl2F3N4O3S
    Biological ActivityRORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), exhibiting an inhibitory concentration (IC50) of 0.428 μM. It has demonstrated efficacy in mitigating Imiquimod-induced psoriasis severity in murine models [1].
    NoteFor research use only
    Expiration Date12 months from date of receipt.
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