RORγt inverse agonist 31

SKU: orb2277919

Description

RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), with an inhibitory concentration (IC50) of 0.428 μM. It has shown efficacy in reducing Imiquimod-induced psoriasis severity in murine models.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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MW	555.36
Formula	C₂₃H₁₅Cl₂F₃N₄O₃S
Target	ROR

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

ROR

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