RORγt inverse agonist 31

• Catalog Number: orb2277919
• Category: Small Molecules
• Description: RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), with an inhibitory concentration (IC50) of 0.428 μM. It has shown efficacy in reducing Imiquimod-induced psoriasis severity in murine models [1].
• Purity: 98.00%
• MW: 555.36
• Formula: C₂₃H₁₅Cl₂F₃N₄O₃S
• Biological Activity: RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), exhibiting an inhibitory concentration (IC50) of 0.428 μM. It has demonstrated efficacy in mitigating Imiquimod-induced psoriasis severity in murine models [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.