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Catalog Number | orb746317 |
---|---|
Category | Small Molecules |
Description | RO2959 is a novel, potent and selective CRAC current inhibitor. RO2959 completely inhibited cytokine production as well as T cell proliferation mediated by TCR stimulation or MLR (mixed lymphocyte reaction). RO2959 potently blocked TCR triggered gene expression and T cell functional pathways similar to CsA and another calcineurin inhibitor FK506. |
CAS Number | [1219927-22-6] |
MW | 463.9318 |
SMILES | O=C(NC1=NC=C(C2=C(C)CCN(C3=NC=C(C)S3)C2)N=C1)C4=C(F)C=CC=C4F.[xHCl] |
Formula | C21H19F2N5OS.xHCl |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1219927-22-6 |
97.42% | |
1219927-22-6 | |
463.93 | |
C21H20ClF2N5OS |
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