RO-3

• Catalog Number: orb611958
• Category: Small Molecules
• Description: RO-3 is a potent, CNS-penetrant, and orally active P2X3 and P2X2/3 antagonist with pIC50s of 5.9 and 7.0 for human homomultimeric P2X3 and heteromultimeric P2X2/3 receptors, respectively. RO-3 shows selectivity for P2X3 and P2X2/3 over all other functional homomultimeric P2X receptors (IC50 > 10 μM at P2X1,2,4,5,7)[1].
• CAS Number: [1026582-88-6]
• MW: 302.37
• SMILES: NC1=NC(N)=NC=C1CC2=C(C(C)C)C=C(OC)C(OC)=C2
• Formula: C₁₆H₂₂N₄O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.