RMC-6291

• Catalog Number: orb1982293
• Category: Small Molecules
• Description: RMC-6291
• CAS Number: 2641998-63-0
• MW: 1012.26
• SMILES: O=C(C#CC(N(C)C)(C)C)N1CCC(F)(C(=O)N(C)C(C(=O)NC2C(=O)N3NC(C(=O)OCC(C)(C)CC=4C5=CC(=CC=C5N(C4C=6C=CC=NC6C(OC)C)CC)N7CCOC(C7)C2)CCC3)C(C)C)CC1
• Formula: C₅₅H₇₈FN₉O₈
• Biological Activity: RMC-6291 is an orally available, highly potent KRASG12C(ON) inhibitor with anticancer and antitumor activity that acts through spatial blockade of RAS effector binding.RMC-6291 blocks ERK signaling and induces apoptosis in KRASG12C-mutant H358 cells.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.