RLX-33

• Catalog Number: orb1687113
• Category: Small Molecules
• Description: RLX-33
• CAS Number: 2784577-71-3
• Purity: 99.82%
• MW: 462.89
• SMILES: O=C(NC=1C=CC(=CC1)C2=NC(=NO2)C=3C=CC(Cl)=CC3)C4CC(=O)N(CC=5OC=CC5)C4
• Formula: C₂₄H₁₉ClN₄O₄
• Biological Activity: RLX-33 is a potent, selective and blood-brain barrier (BBB) penetrant antagonist of relaxin family peptide 3 (RXFP3, IC50=2.36 μM). RLX-33 also blocks relaxin-3-induced ERK1/2 phosphorylation, with IC50s of 7.82 and 13.86 μM for ERK1 and ERK2 phosphorylation, respectively. RLX-33 can inhibits the stimulation of food intake induced by the RXFP3-selective agonist R3/I5 in rats.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.