RLX-33

• Catalog Number: orb1568311
• Category: Small Molecules
• Description: RLX-33 is a potent, selective and blood-brain barrier (BBB) penetrant relaxin family peptide 3 (RXFP3) antagonist, also blocks relaxin-3-induced ERK1/2 phosphorylation, with IC50 values of 2.36 μM for RXFP3, 7.82 and 13.86 μM for ERK1 and ERK2 phosphorylation, respectively. RLX-33 can block the stimulation of food intake induced by the RXFP3-selective agonist R3/I5 in rats. RLX-33 can be used for the research of metabolic syndrome[1].
• CAS Number: [2784577-71-3]
• MW: 462.89
• SMILES: ClC1=CC=C(C2=NOC(C3=CC=C(NC(C4CC(N(CC5=CC=CO5)C4)=O)=O)C=C3)=N2)C=C1
• Formula: C₂₄H₁₉ClN₄O₄
• Note: For research use only
• Expiration Date: 12 months from date of receipt.