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Catalog Number | orb1707087 |
---|---|
Category | Small Molecules |
Description | Ribociclib hydrochloride |
CAS Number | 1211443-80-9 |
MW | 471 |
SMILES | Cl.O=C(C1=CC=2C=NC(=NC2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5)N(C)C |
Formula | C23H31ClN8O |
Biological Activity | Ribociclib hydrochloride is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It is over 1,000-fold less potent against the cyclin B/CDK1 complex. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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