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Catalog Number | orb1307799 |
---|---|
Category | Small Molecules |
Description | Rhosin hydrochloride |
CAS Number | 1281870-42-5 |
Purity | 98.92% |
MW | 431.318 |
SMILES | Cl.Cl.N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N\N=C\C1=CC=C2N=CC=NC2=C1 |
Formula | C20H19ClN6O |
Biological Activity | Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride causes cell apoptosis. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1281870-42-5 |
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