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RGB-286638 free base

RGB-286638 free base

Catalog Number: orb1305572

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$ 140.00
Catalog Numberorb1305572
CategorySmall Molecules
DescriptionRGB-286638 free base
CAS Number784210-88-4
Purity97.29%
MW545.63
SMILESCOCCN1CCN(Cc2ccc(cc2)-c2n[nH]c3-c4cccc(NC(=O)NN5CCOCC5)c4C(=O)c23)CC1
FormulaC29H35N7O4
Biological ActivityRGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 and cyclin D3-CDK6.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.