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Catalog Number | orb1305572 |
---|---|
Category | Small Molecules |
Description | RGB-286638 free base |
CAS Number | 784210-88-4 |
Purity | 97.29% |
MW | 545.63 |
SMILES | COCCN1CCN(Cc2ccc(cc2)-c2n[nH]c3-c4cccc(NC(=O)NN5CCOCC5)c4C(=O)c23)CC1 |
Formula | C29H35N7O4 |
Biological Activity | RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 and cyclin D3-CDK6. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |