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Catalog Number | orb1494709 |
---|---|
Category | Proteins |
Description | Interleukin-2 (IL-2) is a Oglycosylated, four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. |
Form/Appearance | Lyophilized after extensive dialysis against PBS.. |
Purity | > 95% as analyzed by SDS-PAGE. |
MW | 15~16 kDa, observed by reducing SDS-PAGE. |
Protein Sequence | APTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHL RPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT |
Source | CHO |
Biological Activity | ED50 < 2ng/ml, measured in a cell proliferation assay using CTLL-2 cells. |
Endotoxins | < 0.2 EU/μg, determined by LAL method. |
Storage | Lyophilized recombinant Human Interleukin-2 (IL-2) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Interleukin-2 (IL-2) should be stable up to 1 week at 4°C or up to 2 months at -20°C. |
Buffer/Preservatives | Lyophilized after extensive dialysis against PBS.. |
Alternative names | Interleukin-2, IL2 Read more... |
Note | For research use only |
Application notes | Reconstituted in ddH2O or PBS at 100 μg/ml. |
Expiration Date | 6 months from date of receipt. |